Tbk1 protac 3i
Web1 dic 2024 · TBK1 is a noncanonical member of IKK family, and plays a key role in the innate immune system. Earlier structural studies suggest that TBK1 exists as a compact … WebSTING agonist-28 (CF510) is a non-nucleotide small-molecule STING agonist. STING agonist-23 activates STING, increases phosphorylation of STING, TBK1 and IRF3. STING agonist-23 promotes the levels of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells. STING agonist-23 exhibits activity against SARS-CoV series strains. - Mechanism …
Tbk1 protac 3i
Did you know?
WebCat.No. 7259 - TBK1 PROTAC® 3i C53H74BrN9O9S CAS No. 2052306-13-3. Supplier Page. Supplier Page from Tocris Bioscience for TBK1 PROTAC® 3i. Request Info. Product Specs; Company Info; Reviews; Product Specs; Item TBK1 PROTAC® 3i; Company Tocris Bioscience; Price Pricing Info Supplier Page View Company Product Page; WebI-i GRAZIE Siamo lieti che abbiate acquistato questo prodotto KENWOOD e vi diamo il benvenuto al servizio radiomobile privato (PMR 446). PMR è un sistema di …
WebBiological Activity TBK1 PROTAC ® 3i is a potent TANK-binding kinase 1 (TBK1) PROTAC ® Degrader (DC 50 = 12 nM, D max. = 96%).. Exhibits >50-fold selectivity for TBK1 over the closely related IKKε. Comprises a ligand for von-Hippel Lindau (VHL) protein joined by a linker to a TBK1-targeting moiety. WebTBK1 PROTAC® 3i: Specifications: Storage Buffer: Powder: Storage Condition: Store in dry, dark place at -20C for 1 year. Target: Product Information: Molecular Weight: …
WebSDS (Safety Data Sheet) Datasheet. Background. Potent TANK-binding kinase 1 (TBK1) Degrader (DC50 = 12 nM, Dmax = 96%). Exhibits >50-fold selectivity for TBK1 over the … WebShop Tocris Bioscience™ TBK1 PROTAC® 3i at Fishersci.com Tocris Bioscience TBK1 PROTAC 3i 5 mg:Protein Analysis Reagents, Quantity: Fisher Scientific Fisher Scientific
WebCAS#: 2052306-13-3. Description: TBK1 PROTAC® 3i is a Potent TANK-binding kinase 1 (TBK1) Degrader. It exhibits >50-fold selectivity for TBK1 over the closely related IKKε. It …
WebTBK1 PROTAC ® 3i Biological Activity for TBK1 PROTAC ® 3i. TBK1 PROTAC ® 3i is a potent TANK-binding kinase 1 (TBK1) PROTAC ® Degrader... Technical Data for TBK1 … cost share analysisWebTBK1 PROTAC 1 2052306-13-3 A novel potent, selective TBK1 PROTAC with DC50 of 12 nM, selectively degrades TBK1 with excellent selectivity against a related kinase IKKε. supplier price datasheet IC50 chemical structure probechem inhibitor. Welcome to … cost share arrangement transfer pricingWebBiological Activity: Negative control for TBK1 PROTAC® 3i (Cat. No. 7259). Binds TBK1 with high affinity, but exhibits no significant degradation of TBK1. breast cancer pumpkin imagesWebTBK1 control PROTAC ® 4 is a negative control for TBK1 PROTAC ® 3i (Cat. No. 7259). Binds TBK1 with high affinity, but exhibits no significant degradation of TBK1. PROTAC … breast cancer pumpkin contestbreast cancer pumpkin carving ideasWeb19 ago 2015 · Introduction: TANK-binding kinase 1 (TBK1) is a noncanonical IκB kinase family member that regulates the innate immune response. Misregulation of TBK1 activity can promote inflammatory disorders and oncogenesis; therefore, TBK1 inhibitors are considered a promising therapy for inflammation and cancer. breast cancer pumpkin decorating ideasWebTBK1 control PROTAC ® 4 is a negative control for TBK1 PROTAC ® 3i (Cat. No. 7259). Binds TBK1 with high affinity, but exhibits no significant degradation of TBK1. … breast cancer pyramid pix2pix paperwith code