WebMay 20, 2024 · The results showed that cryptotanshinone could reduce the tumor mass, increase the tumor suppression rate, and enhance the chemotherapeutic effect of 5-fluorouracil by a mechanism related to inhibition of the Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway. Expand. View 1 excerpt, cites background; WebProvided are a composition for stimulating differentiation of MSCs into osteoblasts, which includes cryptotanshinone, and an osteogenesis stimulator including cryptotanshinone and MSCs. When the cryptotanshinone is treated to the MSCs, the differentiation into osteoblasts is stimulated, and thus osteogenesis of a patient may be stimulated by …
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WebAug 13, 2024 · Hepatocellular carcinoma (HCC) is a fatal and dominant form of liver cancer that currently has no effective treatment or positive prognosis. In this study, we explored the antitumor effects of cryptotanshinone (CPT) against HCC and the molecular mechanisms underlying these effects using a systems pharmacology and experimental validation … Web建立了高效液相色谱法测定复方丹参片中丹参酮ⅡA的方法。方法简便、准确、灵敏度高、重现性好,共存组份无干扰。经考察市售七个生产厂家的产品,含量差异非常显著,提示生产厂家应在原料药材与生产过程中注意丹参酮ⅡA的含量。建议对复方丹参片进行丹参酮ⅡA的含量 … crystal hospitality
Frontiers The Anticancer Properties of Tanshinones and the ...
WebThe nature of intestinal absorption of most herbal medicine is unknown. Cryptotanshinone (CTS) is the principal active constituent of the widely used cardiovascular herb Salvia miltiorrhiza (Danshen). We investigated the oral bioavailability of CTS in rats and the mechanism for its intestinal absorption using several in vitro and in vivo models: 1) Caco … WebCryptotanshinone C19H20O3 CID 160254 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities ... WebCryptotanshinone is a quinoid diterpene isolated from the root of the Asian medicinal plant, Salvia miotiorrhiza bunge. Recently it was discovered that the compound is a potent STAT3 inhibitor. Cryptotanshinone rapidly inhibited STAT3 Tyr705 phosphorylation through a JAK2-independent mechanism. Cryptotanshinone selectively inhibits STAT3 ... crystal horse head statue